Instruments that involve math-like operations or calibration just cow me and I have stared at this thing for as long as I have owned it.
I didn't know how to use it until I helped judge the honey contest with a certified Welsh honey judge in West Palm Beach at the Southeastern Organic Beekeepers Conference. Dr. Mikhail Kruglyakov taught me what to do. Thanks so much to him for his lesson.
So for any of you equally intimidated by the refractometer, here's a simple lesson in how to use it to measure the moisture content in your honey.
This is what the instrument looks like. The eyepiece is on the left end and the place for the honey is on the right.

You lift the plastic cover like so:

There's a pipette to use to place the droplet of honey on the refractometer, although I sometimes use a chop stick.

Then like in chemistry lab, you place the plastic top down on top of the droplet, flattening it on the viewing window.

I can't take a picture of the next step, which for me is first put on my glasses, then look through the eyepiece with the instrument held up toward the light. Then focus by twisting the dial near the eyepiece until you can read the chart. There you'll see the good or bad news. The chart indicates the moisture level which you want to be at about 18.6%.
At first the reason that I thought I couldn't use the thing is that I didn't know I could focus it - so I would diligently put on my glasses, hold the loaded refractometer up to the light and see only a blur through the lens.
I thought something must be wrong - and it was - I hadn't focused the eyepiece!